1-(5-Aminopyridin-2-yl)pyrrolidin-3-ol → 2-(2-bromophenyl)-N-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide

HRID 148273Notes

Reaction equation

HRID 148273 reaction equation
[Br:1][c:2]1[c:3](-[c:8]2[o:9][c:10]([C:16]([F:17])([F:18])[F:19])[c:11]([C:13](=[O:14])[OH:15])[n:12]2)[cH:4][cH:5][cH:6][cH:7]1.[NH2:20][c:21]1[cH:22][cH:23][c:24]([N:27]2[CH2:28][CH:29]([OH:32])[CH2:30][CH2:31]2)[n:25][cH:26]1>>[Br:1][c:2]1[c:3](-[c:8]2[o:9][c:10]([C:16]([F:17])([F:18])[F:19])[c:11]([C:13](=[O:15])[NH:20][c:21]3[cH:22][cH:23][c:24]([N:27]4[CH2:28][CH:29]([OH:32])[CH2:30][CH2:31]4)[n:25][cH:26]3)[n:12]2)[cH:4][cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 534081671-(5-Aminopyridin-2-yl)pyrrolidin-3-olHCID 59301376HCID 59301376, compound

Product 1

HCID 1785221852-(2-bromophenyl)-N-[6-(3-hydroxypyrrolidin-1-yl)-3-pyridinyl]-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide

Sources & evidence

ORD record
ord-466ea8b0d01f440c887fbde29d5f4c6d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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