1,2,4-Trimethylbenzene → HCID 13887927, compound

Participants

Reaction Conditions

Reaction Steps

5% Palladium on carbon (11 g), 6-ethylidene-2,2-dimethylcyclohexan-1-one (415 g) and pseudocumene (390 g) were charged in a reactor. The reactor was purged with N2 gas. The reaction mixture was heated to 170° C. and acid formic (3 g) was added over 15 h. The reactor was cool down. The reaction mixture was filtrated and distilled under reduced pressure afforded 2-ethyl-6,6-dimethylcyclohex-2-en-1-one (394 g, 93% yield).

Provenance & Evidence