3-(4-Hydroxyphenyl)propionic acid → HCID 58446581, compound
Reaction equation
OC1C=CC(O[CH2:7][C:8]([O:10][CH2:11][CH2:12][C:13]2[CH:18]=[CH:17][C:16]([OH:19])=[CH:15][CH:14]=2)=[O:9])=CC=1.C(C(O)=O)[CH2:23][C:24]1[CH:29]=[CH:28][C:27]([OH:30])=[CH:26][CH:25]=1>>[OH:30][C:27]1[CH:28]=[CH:29][C:24]([CH2:23][CH2:7][C:8]([O:10][CH2:11][CH2:12][C:13]2[CH:14]=[CH:15][C:16]([OH:19])=[CH:17][CH:18]=2)=[O:9])=[CH:25][CH:26]=1Participants
3
Procedure
Using a similar procedure, 4-hydroxyphenethyl 2-(4-hydroxyphenoxy)acetate (compound of Formula (V) where L1=bond, L4=—O—, m=2, n=1, y1=y2=0) is prepared by substituting 2-(4-hydroxyphenoxy)acetic acid for desaminotyrosine. Similar results are obtained.
Workup
- customis prepared
- customSimilar results
- customare obtained
Sources & evidence
- ORD record
- ord-35ffc71ab7424534aca0e732f325ea6b
- Source dataset
- uspto-grants-2016_08
- Patent number
- US09416090B2
Reaction notes
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