HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 49839964, compound → HCID 58315418, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 49839964 | HCID 49839964 | — |
| Reactant | 2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide | HCID 58315432 | — |
| Product | HCID 58315418 | HCID 58315418 | 46% |
Reaction Steps
Following General Procedure D, 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide (200 mg, 0.68 mmol) and 4-(6-amino-pyridazin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester (210 mg, 0.75 mmol) to give 4-[6-(7-cyclopentyl-6-dimethylcarbamoyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-pyridazin-3-yl]-piperazine-1-carboxylic acid tert-butyl ester (150 mg, 46%). MS (ESI) m/z 536.3 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09416136B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-8a345d382e7144d6b328eac90ee31cfa |
| Source note | uspto-grants-2016_08 |