HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 90266380, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2,5-Dibromopyridine | HCID 69353 | — |
| Reactant | HCID 84038454 | HCID 84038454 | — |
| Reactant | HCID 86727233 | HCID 86727233 | — |
| Catalyst | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| Catalyst | Bis(dibenzylideneacetone)palladium | HCID 9811564 | — |
| Product | HCID 90266380 | HCID 90266380 | 70% |
Reaction Steps
Compound 25a (927 mg, 2.73 mmol), 2,5-dibromopyridine (500 mg, 2.1 mmol, cesium carbonate (1.03 g, 3.15 mmol), Pd2(dba)3 (100 mg, 0.1 mmol) and xantphos (73 mg, 0.13 mmol), reacted following the synthetic method of compound 19a to afford 750 mg of viscous liquid, yield 70%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09416144B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-5d2ef78942984a5aa7592403f10a7197 |
| Source note | uspto-grants-2016_08 |