Acetyl chloride → 3-({Acetyl-[3-(2-chloro-pyrimidin-4-yl)-benzyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Participants

Role	Name	HCID	Charge
Reactant	Acetyl chloride	HCID 6367	—
Reactant	3-{[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-methyl}-pyrrolidine-1-carboxylic acid tert-butyl ester	HCID 86603279	—
Product	3-({Acetyl-[3-(2-chloro-pyrimidin-4-yl)-benzyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester	HCID 86603280	—

Intermediate 59 was coupled with acetyl chloride following procedure D. LC-MS showed the product had the expected M+H+ of 445.