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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1483893Generated: October 31, 2026

Hydrochloric Acid → 1-Butyl-4-(3-trifluoromethyl-phenyl)piperidine

https://huagongshe.com/reaction/1483893

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantButyl bromideHCID 8002—
Reactant4-(3-(Trifluoromethyl)Phenyl)PiperidineHCID 11736340—
Product1-Butyl-4-(3-trifluoromethyl-phenyl)piperidineHCID 22397849—

Reaction Steps

Beginning with 4-(3-Trifluoromethyl-phenyl)-piperidine and n-Bu-Br: m.p. 222° C. (HCl), MS m/z (rel. intensity, 70 eV) 285 (M+, 3), 243 (12), 242 (bp), 70 (51), 56 (17).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE046117E1
Source datasetuspto-grants-2016_08
ORD IDord-a359e951fcea4fda9fa944fdb655bd9b
Source noteuspto-grants-2016_08