1-Cyanocyclopropanecarboxylic acid → HCID 53248188, compound

HRID 1484067Notes

Reaction equation

HRID 1484067 reaction equation
[CH:1]1([CH2:7][O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]2[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][CH:17]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:23]([C:25]1([C:28](O)=[O:29])[CH2:27][CH2:26]1)#[N:24]>>[C:23]([C:25]1([C:28]([NH:20][C:19]2[CH:21]=[CH:22][C:16]([CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][O:8][CH2:7][CH:1]3[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)=[CH:17][CH:18]=2)=[O:29])[CH2:27][CH2:26]1)#[N:24]

Participants

3

Reactant 2

HCID 27332591-Cyanocyclopropanecarboxylic acidHCID 53248183HCID 53248183, compound

Product 1

HCID 53248188HCID 53248188, compoundYield 96%

Procedure

General procedure E was used to convert 0.616 mmol of 13 and 0.924 mmol of 1-cyanocyclopropanecarboxylic acid to 0.590 mmol (96%) of the title compound.

Sources & evidence

ORD record
ord-7679c7ffefec474493ff582fdd02abaa
Source dataset
uspto-grants-2016_08
Patent number
US09421177B2

Reaction notes

Loading…