1-Cyanocyclopropanecarboxylic acid → HCID 53248186, compound

HRID 1484069Notes

Reaction equation

HRID 1484069 reaction equation
[CH2:1]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]1[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][CH:17]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:23]([C:25]1([C:28](O)=[O:29])[CH2:27][CH2:26]1)#[N:24]>>[CH2:1]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]1[CH:17]=[CH:18][C:19]([NH:20][C:28]([C:25]2([C:23]#[N:24])[CH2:27][CH2:26]2)=[O:29])=[CH:21][CH:22]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 27332591-Cyanocyclopropanecarboxylic acidHCID 53248136HCID 53248136, compound

Product 1

HCID 53248186HCID 53248186, compoundYield 98.1%

Procedure

General procedure E was used to convert 1.05 mmol of 13a and 1.575 mmol of 1-cyanocyclopropanecarboxylic acid to 1.03 mmol (98%) of the title compound.

Sources & evidence

ORD record
ord-368f95ac89134cbdb64057442760a9c9
Source dataset
uspto-grants-2016_08
Patent number
US09421177B2

Reaction notes

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