1-Cyanocyclopropanecarboxylic acid → HCID 53248187, compound

HRID 1484071Notes

Reaction equation

HRID 1484071 reaction equation
[CH:1]1([CH2:7][O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][C:15]2[CH:21]=[CH:20][C:18]([NH2:19])=[CH:17][CH:16]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:22]([C:24]1([C:27](O)=[O:28])[CH2:26][CH2:25]1)#[N:23]>>[C:22]([C:24]1([C:27]([NH:19][C:18]2[CH:20]=[CH:21][C:15]([CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][O:8][CH2:7][CH:1]3[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)=[CH:16][CH:17]=2)=[O:28])[CH2:26][CH2:25]1)#[N:23]

Participants

3

Reactant 2

HCID 27332591-Cyanocyclopropanecarboxylic acidHCID 53248182HCID 53248182, compound

Product 1

HCID 53248187HCID 53248187, compoundYield 99.2%

Procedure

General procedure E was used to convert 1.30 mmol of 13b and 1.95 mmol of 1-cyanocyclopropanecarboxylic acid to 1.29 mmol (99%) of the title compound.

Sources & evidence

ORD record
ord-0db3246830e74bbc8d54a6854c18c99b
Source dataset
uspto-grants-2016_08
Patent number
US09421177B2

Reaction notes

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