1-Bromo-4-nitrobenzene → 1-[8-(Cyclohexylmethoxy)octyl]-4-nitrobenzene

HRID 1484072Notes

Reaction equation

HRID 1484072 reaction equation
[CH2:1]([O:9][CH2:10][CH:11]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH:7]=[CH2:8].Br[C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1>>[CH:11]1([CH2:10][O:9][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][C:18]2[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=2)[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1

Participants

3

Reactant 2

HCID 114661-Bromo-4-nitrobenzeneHCID 53248071HCID 53248071, compound

Product 1

HCID 532481341-[8-(Cyclohexylmethoxy)octyl]-4-nitrobenzeneYield 48%

Procedure

General procedure M was used to convert 4.56 mmol of 11c and 5.02 mmol of 1-bromo-4-nitrobenzene to 2.19 mmol (48%) of the title compound.

Sources & evidence

ORD record
ord-01e8a4ddc11f4708b2ed5c0c173e25d4
Source dataset
uspto-grants-2016_08
Patent number
US09421177B2

Reaction notes

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