1-Cyanocyclopropanecarboxylic acid → HCID 53248321, compound

HRID 1484077Notes

Reaction equation

HRID 1484077 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]2[CH:22]=[CH:21][C:19]([NH2:20])=[CH:18][CH:17]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:23]([C:25]1([C:28](O)=[O:29])[CH2:27][CH2:26]1)#[N:24]>>[C:23]([C:25]1([C:28]([NH:20][C:19]2[CH:18]=[CH:17][C:16]([CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[CH:22][CH:21]=2)=[O:29])[CH2:27][CH2:26]1)#[N:24]

Participants

3

Reactant 2

HCID 27332591-Cyanocyclopropanecarboxylic acidHCID 14931619HCID 14931619, compound

Product 1

HCID 53248321HCID 53248321, compoundYield 94%

Procedure

General procedure E was used to convert 2.56 mmol of 17 and 3.84 mmol of 1-cyanocyclopropanecarboxylic acid to 2.40 mmol (94%) of the title compound.

Sources & evidence

ORD record
ord-1fb81a21a579400fb7faf199e40591c6
Source dataset
uspto-grants-2016_08
Patent number
US09421177B2

Reaction notes

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