Dichlorodimethylsilane → Diacetoxydimethylsilane

HRID 1484200Notes

Reaction equation

HRID 1484200 reaction equation
[C:1]([O-:4])(=[O:3])[CH3:2].[Na+].[CH3:6][Si:7]([CH3:10])(Cl)Cl>C(OCC)C>[C:1]([O:4][Si:7]([O:4][C:1](=[O:3])[CH3:2])([CH3:10])[CH3:6])(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 6398DichlorodimethylsilaneHCID 517045Sodium Acetate

Product 1

HCID 75130DiacetoxydimethylsilaneYield 70%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

To a slurry of sodium acetate (8.2 g, 100 mmol, 2.0 equiv.) in anhydrous diethyl ether (40 mL) was slowly added a solution of dimethyldichloro silane 11A (6.45 g, 50 mmol, 1.0 equiv.) in anhydrous diethyl ether (10 mL). After addition was completed, the mixture was heated at reflux for 2 hours, and then filtered under N2. The filtrate was concentrated under vacuum at 40° C. to give diacetate 11B as a colorless oil (6.1 g, 70%).

Workup

  1. additionAfter addition
  2. temperaturethe mixture was heated
  3. temperatureat reflux for 2 hours
  4. filtrationfiltered under N2
  5. concentrationThe filtrate was concentrated under vacuum at 40° C.

Sources & evidence

ORD record
ord-044d23d5fb2446ff94e171865cff9bb3
Source dataset
uspto-grants-2016_08
Patent number
US09421273B2

Reaction notes

Loading…