HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonamide, 4-amino-N,N-dimethyl- → HCID 178486141, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonamide, 4-amino-N,N-dimethyl- | HCID 74369 | — |
| Reactant | 3-(4-(3-cyclopropyl-1H-pyrazol-5-ylamino)pyrimidin-2-ylamino)benzenesulfonamide | HCID 178514714 | — |
| Product | HCID 178486141 | HCID 178486141 | 9.8% |
Reaction Steps
Compound 103 (25.0 mg, 9.8%) was prepared from 4-amino-N,N-dimethylbenzenesulfonamide as described in Compound 82 and purified by prep HPLC. LC-MS (m/z): 400.1 [M+H]+; 1H NMR (400 MHz, DMSO-d6): δ 0.69-0.73 (m, 2H), 0.91-0.96 (m, 2H), 1.86-1.90 (m, 1H), 2.58 (s, 6H), 6.28 (bs, 1H), 6.54 (bs, 1H), 7.60 (d, J=4.0 Hz, 2H), 8.04 (d, J=4.0 Hz, 3H), 9.66 (s, 2H), 12.08 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422271B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-1bd71ea69d584002a1fae9639cc313c7 |
| Source note | uspto-grants-2016_08 |