HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Iodosuccinimide → HCID 178517799, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | HCID 178516525 | HCID 178516525 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178517799 | HCID 178517799 | 95.2% |
Reaction Steps
A mixture of pyrimidine-2,4-diol (100 g, 0.892 mol) and NIS (220 g, 1.981 mol, 1.1 eq) in AcOH (900 mL) was stirred for about 7 h. Solid 5-iodopyrimidine-2,4-diol (202 g, 95%) was obtained by filtration, washed with ethyl acetate. LC-MS (m/z)=238.9 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422271B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-ae3b1112ff9748ebabde73dc2fc90ed8 |
| Source note | uspto-grants-2016_08 |