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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 148490Generated: October 27, 2026

Toluene → 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-methyl-1-{6-[4-(4-methyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-urea

https://huagongshe.com/reaction/148490

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantPhosgeneHCID 6371—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 56594745HCID 56594745—
Reactant2,6-Dichloro-3,5-dimethoxyanilineHCID 59486253—
Product3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-methyl-1-{6-[4-(4-methyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-ureaHCID 57710325—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-cd31eaec10fa4a56a4a1504e032f6611
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)