Diethyl Ether → HCID 23677780, compound

To a cooled suspension of 54.0 g. (1 mole) of sodium methoxide in a liter of dry ether, a mixture of 80 ml. (1.3 moles) of methylformate and 76 ml. (1 mole) of y-butyrolactone was added dropwise with stirring over a 2-h period. The stirring was continued at room temperature overnight. The reaction mixture was then cooled in an ice bath for 1 hr. to complete the separation of the cream-colored product which was then collected, washed with dry ether, and dried under vacuum to yield sodium (Z)-(2-oxodihydrofuran-3(2H)-ylidene)methanolate (123 g, 90%)

1. additionTo a cooled suspension of 54.0 g
2. temperatureThe reaction mixture was then cooled in an ice bath for 1 hr
3. customthe separation of the cream-colored product which
4. customwas then collected
5. washwashed with dry ether
6. customdried under vacuum

ORD record

ord-833a8a94f03e4faeaa5874fd0f1df08f

Source dataset

uspto-grants-2016_08

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US09422271B2