3-(Trifluoromethyl)phenethylic alcohol → [4-(Trifluoromethyl)phenyl]acetaldehyde

HRID 1485071Notes

Reaction equation

HRID 1485071 reaction equation
FC(F)(F)C1C=C(C=CC=1)CCO.[F:14][C:15]([F:26])([F:25])[C:16]1[CH:24]=[CH:23][C:19]([CH2:20][CH2:21][OH:22])=[CH:18][CH:17]=1>>[F:14][C:15]([F:25])([F:26])[C:16]1[CH:17]=[CH:18][C:19]([CH2:20][CH:21]=[O:22])=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 959263-(Trifluoromethyl)phenethylic alcoholHCID 112755102-(4-(Trifluoromethyl)phenyl)ethan-1-ol

Product 1

HCID 14298210[4-(Trifluoromethyl)phenyl]acetaldehyde

Procedure

Instead of 3-(trifluoromethyl)phenethyl alcohol, 4-(trifluoromethyl)phenethyl alcohol was used and treated by the same technique as in Reference Example 19-1 to give the titled compound as a yellow oil.

Workup

  1. additiontreated by the same technique as in Reference Example 19-1

Sources & evidence

ORD record
ord-a060dacae02f4ff59eae961e8cae073a
Source dataset
uspto-grants-2016_08
Patent number
US09422240B2

Reaction notes

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