HCID 58020631, compound → HCID 58020608, compound

HRID 1485072Notes

Reaction equation

HRID 1485072 reaction equation
BrC1C=CC(OC2N=C[C:10]([CH:13]=O)=[CH:9]C=2)=CC=1.[F:17][C:18]([F:38])([F:37])[C:19]1[CH:28]=[CH:27][C:22]([C:23]([O:25][CH3:26])=[O:24])=[CH:21][C:20]=1OS(C(F)(F)F)(=O)=O>>[CH:13]1([C:20]2[CH:21]=[C:22]([CH:27]=[CH:28][C:19]=2[C:18]([F:38])([F:37])[F:17])[C:23]([O:25][CH3:26])=[O:24])[CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 58020631HCID 58020631, compoundHCID 80632509HCID 80632509, compound

Product 1

HCID 58020608HCID 58020608, compound

Procedure

Instead of 6-(4-bromophenoxy)pyridine-3-carbaldehyde, methyl 4-(trifluoromethyl)-3-{[(trifluoromethyl)sulfonyl]oxy}benzoate (see WO 2007/129745) (2.21 g) was used and treated by the same technique as in Reference Example 13-37(2) to give methyl 3-cyclopropyl-4-(trifluoromethyl)benzoate as a colorless oil (1.42 g).

Workup

  1. additiontreated by the same technique as in Reference Example 13-37(2)

Sources & evidence

ORD record
ord-7b3579ce17184834b03f41866b2735c9
Source dataset
uspto-grants-2016_08
Patent number
US09422240B2

Reaction notes

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