3-Phenylcyclobutanone → HCID 178521034, compound

HRID 1485084Notes

Reaction equation

HRID 1485084 reaction equation
C1(C2C[C:9](=[O:11])C2)C=CC=CC=1.[F:12][C:13]1[CH:18]=[CH:17][C:16]([CH:19]2[CH2:22][C:21](=O)[CH2:20]2)=[CH:15][CH:14]=1>>[F:12][C:13]1[CH:18]=[CH:17][C:16]([C@H:19]2[CH2:22][C@H:21]([CH:9]=[O:11])[CH2:20]2)=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 1429633-PhenylcyclobutanoneHCID 114125713-(4-Fluorophenyl)cyclobutan-1-one

Product 1

HCID 178521034HCID 178521034, compound

Procedure

Instead of 3-phenylcyclobutanone, 3-(4-fluorophenyl)cyclobutanone (4.63 g) was used and treated by the same technique as in Reference Example 24-1 to give the titled compound as a colorless oil (720 mg).

Workup

  1. additiontreated by the same technique as in Reference Example 24-1

Sources & evidence

ORD record
ord-57799256a8154451952fcaf7affda71a
Source dataset
uspto-grants-2016_08
Patent number
US09422240B2

Reaction notes

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