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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1485097Generated: October 31, 2026

4-Hydroxybenzaldehyde → HCID 178472489, compound

https://huagongshe.com/reaction/1485097

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-HydroxybenzaldehydeHCID 126—
Reactant1-(Bromomethyl)-4-chlorobenzeneHCID 69329—
ReactantEthyl 4-hydroxycyclohexanecarboxylateHCID 86973—
Reactant(Bromomethyl)cyclobutaneHCID 2734658—
ProductHCID 178472489HCID 178472489—
ProductHCID 178472490HCID 178472490—

Reaction Steps

Instead of 4-hydroxybenzaldehyde and (bromomethyl)cyclobutane, ethyl 4-hydroxycyclohexanecarboxylate (2.00 g) and 4-chlorobenzylbromide (2.86 g) were respectively used and treated by the same technique as in Reference Example 9-1 to give ethyl cis-4-[(4-chlorobenzyl)oxy]cyclohexanecarboxylate as a colorless oil (0.33 g) and ethyl trans-4-[(4-chlorobenzyl)oxy]cyclohexanecarboxylate as a pale yellow oil (0.47 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09422240B2
Source datasetuspto-grants-2016_08
ORD IDord-aed76dc29433422586c1689c0fbca0d6
Source noteuspto-grants-2016_08