HCID 18340789, compound → HCID 178520993, compound

HRID 1485098Notes

Reaction equation

HRID 1485098 reaction equation
[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([CH2:6][O:7][C@H:8]2[CH2:13][CH2:12][C@H:11]([C:14](OCC)=[O:15])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.C(OC(NC1(CC(OC)=O)CC(=O)NC1)=O)C1C=CC=CC=1>>[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([CH2:6][O:7][C@H:8]2[CH2:9][CH2:10][C@H:11]([CH:14]=[O:15])[CH2:12][CH2:13]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 18340789HCID 18340789, compoundHCID 178472490HCID 178472490, compound

Product 1

HCID 178520993HCID 178520993, compoundYield 53.2%

Procedure

The ethyl trans-4-[(4-chlorobenzyl)oxy]cyclohexanecarboxylate (856 mg) obtained in Reference Example 36-1(1) was used and treated by the same techniques as in Reference Example 36-1(2) and (3) to give the titled compound as a yellow oil (388 mg).

Sources & evidence

ORD record
ord-02a6de39c79947c389e0c3a34b201184
Source dataset
uspto-grants-2016_08
Patent number
US09422240B2

Reaction notes

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