HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzaldehyde → HCID 118113224, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | Bromocyclopropane | HCID 78037 | — |
| Reactant | 4-(Bromomethyl)benzonitrile | HCID 86996 | — |
| Reactant | 5-Hydroxy-2-(trifluoromethyl)pyridine | HCID 2783388 | — |
| Product | HCID 118113224 | HCID 118113224 | 96.7% |
Reaction Steps
Instead of 4-hydroxybenzaldehyde and bromocyclopropane, 6-(trifluoromethyl)pyridin-3-ol (1.21 g) and 4-cyanobenzylbromide (1.45 g) were respectively used and treated by the same technique as in Reference Example 10-1 to give 4-({[6-(trifluoromethyl)pyridin-3-yl]oxy}methyl)benzonitrile as a pale brown solid (1.99 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422240B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-79f3caaa09b4459ea6cc86983b613a99 |
| Source note | uspto-grants-2016_08 |