Sodium Hydroxide → HCID 118113264, compound

HRID 1485126Notes

Reaction equation

HRID 1485126 reaction equation
[Cl:1][C:2]1[CH:30]=[CH:29][C:5]([O:6][C:7]2[N:12]=[CH:11][C:10]([CH2:13][N:14]3[CH2:19][CH2:18][C:17]([OH:20])=[C:16]([C:21]([NH:23][CH2:24][C:25]([OH:27])=[O:26])=[O:22])[C:15]3=[O:28])=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.[OH-].[Na+:32]>CC(C)=O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:6][C:7]2[N:12]=[CH:11][C:10]([CH2:13][N:14]3[CH2:19][CH2:18][C:17]([OH:20])=[C:16]([C:21]([NH:23][CH2:24][C:25]([O-:27])=[O:26])=[O:22])[C:15]3=[O:28])=[CH:9][CH:8]=2)=[CH:29][CH:30]=1.[Na+:32]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 73052863TP0463518

Product 1

HCID 118113264HCID 118113264, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution in acetone of the compound (645 mg) obtained in step (2) above, 1 mol/L sodium hydroxide in aqueous solution (1.50 mL) was added and the mixture was stirred at room temperature for 30 minutes. The resulting precipitate was recovered by filtration to give the titled compound as a colorless solid (543 mg).

Workup

  1. filtrationThe resulting precipitate was recovered by filtration

Sources & evidence

ORD record
ord-086877f38ba94a35840ee2866beed512
Source dataset
uspto-grants-2016_08
Patent number
US09422240B2

Reaction notes

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