Methanol → 3-Methyl-4-(5-thiophen-3-yl-thiazol-2-ylamino)-phenol

HRID 148526Notes

Reaction equation

HRID 148526 reaction equation
[B:48]([Br:49])([Br:50])[Br:51].[CH3:28][O:29][c:30]1[cH:31][c:32]([CH3:47])[c:33]([NH:36][c:37]2[s:38][c:39](-[c:42]3[cH:43][s:44][cH:45][cH:46]3)[cH:40][n:41]2)[cH:34][cH:35]1.[CH3:55][OH:56].[Cl:52][CH2:53][Cl:54].[N:1]1([CH2:2][CH2:3][O:4][c:5]2[cH:6][cH:7][c:8]([NH:9][c:10]3[s:11][c:12](-[c:13]4[cH:14][cH:15][c:16]([OH:17])[cH:18][cH:19]4)[cH:20][n:21]3)[cH:22][cH:23]2)[CH2:24][CH2:25][CH2:26][CH2:27]1>>[OH:29][c:30]1[cH:31][c:32]([CH3:47])[c:33]([NH:36][c:37]2[s:38][c:39](-[c:42]3[cH:43][s:44][cH:45][cH:46]3)[cH:40][n:41]2)[cH:34][cH:35]1

Participants

6

Reactant 5

HCID 887MethanolHCID 6344DichloromethaneHCID 25134Boron tribromideHCID 111882064-{2-[4-(2-Pyrrolidin-1-yl-ethoxy)-phenylamino]-thiazol-5-yl}-phenolHCID 58923520(4-Methoxy-2-methyl-phenyl)-(5-thiophen-3-yl-thiazol-2-yl)-amine

Product 1

HCID 589235083-Methyl-4-(5-thiophen-3-yl-thiazol-2-ylamino)-phenol

Sources & evidence

ORD record
ord-0f8a29d1bc6e462580d86b48dfb3c90e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…