HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane hydrochloride → 76391-36-1
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane hydrochloride | HCID 20443148 | — |
| Reactant | (2S,4R)-1-tert-butyl 2-methyl 4-methoxypyrrolidine-1,2-dicarboxylate | HCID 58984985 | — |
| Product | 76391-36-1 | HCID 55254182 | — |
Reaction Steps
A solution of (2S,4R)-1-tertbutoxycarbonyl-2-methoxycarbonyl-4-methoxy pyrrolidine (9 g, 34.74 mmol) in 4 M HCl-dioxane (13 mL) was stirred at RT overnight. The reaction mixture was concentrated to dryness, washed with hexane followed by ether and dried under vacuum to afford (2S,4R)-methyl 4-methoxypyrrolidine-2-carboxylate hydrochloride (6 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422267B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-f62894f887324844a0d324f6b7b5f287 |
| Source note | uspto-grants-2016_08 |