HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-boronobenzenesulfonamide → 3-(4-amino-2-chlorothieno[3,2-d]pyrimidin-7-yl)-N-methylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-boronobenzenesulfonamide | HCID 44886921 | — |
| Reactant | 7-Bromo-2-chlorothieno[3,2-d]pyrimidin-4-amine | HCID 86675650 | — |
| Product | 3-(4-amino-2-chlorothieno[3,2-d]pyrimidin-7-yl)-N-methylbenzenesulfonamide | HCID 86675654 | 71.2% |
Reaction Steps
The target compound (480 mg, 71% yield) was prepared in the same manner as Step 1 of Example 11 using 7-bromo-2-chlorothieno[3,2-d]pyrimidin-4-amine (500 mg, 1.90 mmol) and 3-(N-methylsulfamoyl)phenylboronic acid (409 mg, 1.90 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422307B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-c5aa2db9f31e42d9b0334b1599b23794 |
| Source note | uspto-grants-2016_08 |