HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminophenylboronic acid → 7-(3-Aminophenyl)-2-chlorothieno[3,2-d]pyrimidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminophenylboronic acid | HCID 92269 | — |
| Reactant | 7-Bromo-2-chlorothieno[3,2-d]pyrimidin-4-amine | HCID 86675650 | — |
| Product | 7-(3-Aminophenyl)-2-chlorothieno[3,2-d]pyrimidin-4-amine | HCID 86675655 | 68.5% |
Reaction Steps
The target compound (360 mg, 68% yield) was prepared in the same manner as Step 1 of Example 11 using 7-bromo-2-chlorothieno[3,2-d]pyrimidin-4-amine (500 mg, 1.90 mmol) and 3-aminophenylboronic acid (261 mg, 1.90 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422307B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-1e0b589b524d451c8d9b6eccfb9e51d0 |
| Source note | uspto-grants-2016_08 |