6-(4-Ethylpiperazin-1-yl)pyridin-3-amine → N-(3-(4-amino-2-(6-(4-ethylpiperazin-1-yl)pyridin-3-ylamino)thieno[3,2-d]pyrimidin-7-yl)phenyl)methanesulfonamide

Participants

Reaction Steps

The target compound of Example 27 (22 mg, 74% yield) was prepared in the same manner as Step 9 of Example 1 using N-(3-(4-amino-2-chlorothieno[3,2-d]pyrimidin-7-yl)phenyl)methanesulfonamide (20 mg, 0.056 mmol) and 6-(4-ethylpiperazin-1-yl)pyridin-3-amine (31 mg, 0.17 mmol).

Provenance & Evidence