HuagongsheHuagongshe Chemistry Print Report · For research reference only
Quinoline-3-boronic acid → 2-Chloro-7-(quinolin-3-yl)thieno[3,2-d]pyrimidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Quinoline-3-boronic acid | HCID 2734663 | — |
| Reactant | 7-Bromo-2-chlorothieno[3,2-d]pyrimidin-4-amine | HCID 86675650 | — |
| Product | 2-Chloro-7-(quinolin-3-yl)thieno[3,2-d]pyrimidin-4-amine | HCID 86675657 | 43.8% |
Reaction Steps
The target compound (260 mg, 43% yield) was prepared in the same manner as Step 1 of Example 11 using 7-bromo-2-chlorothieno[3,2-d]pyrimidin-4-amine (500 mg, 1.90 mmol) and quinolin-3-ylboronic acid (329 mg, 1.90 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422307B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-ebb48133a35f447dac16486a9e591546 |
| Source note | uspto-grants-2016_08 |