HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenethylamine, (+)- → (R)-7-bromo-2-chloro-N-(1-phenylethyl)thieno[3,2-d]pyrimidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenethylamine, (+)- | HCID 643189 | — |
| Reactant | 7-Bromo-2,4-dichlorothieno[3,2-d]pyrimidine | HCID 18326422 | — |
| Product | (R)-7-bromo-2-chloro-N-(1-phenylethyl)thieno[3,2-d]pyrimidin-4-amine | HCID 86675660 | 83% |
Reaction Steps
The target compound (540 mg, 83% yield) was prepared in the same manner as Step 1 of Example 44 using 7-bromo-2,4-dichlorothieno[3,2-d]pyrimidine (500 mg, 1.77 mmol) and (R)-1-phenylethanamine (0.68 mL, 5.31 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422307B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-5e44020d9af242eca0592a05214ec008 |
| Source note | uspto-grants-2016_08 |