HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Morpholinoethylamine → N4-benzyl-N2-(2-morpholinoethyl)-7-vinylthieno[3,2-d]pyrimidin-2,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Morpholinoethylamine | HCID 408285 | — |
| Reactant | N-benzyl-2-chloro-7-vinylthieno[3,2-d]pyrimidin-4-amine | HCID 86675661 | — |
| Product | N4-benzyl-N2-(2-morpholinoethyl)-7-vinylthieno[3,2-d]pyrimidin-2,4-diamine | HCID 53239540 | 78.5% |
Reaction Steps
The target compound of Example 46 (36 mg, 78% yield) was prepared in the same manner as Step 3 of Example 44 using N-benzyl-2-chloro-7-vinylthieno[3,2-d]pyrimidin-4-amine (35 mg, 0.116 mmol) and 2-morpholinoethanamine (75 mg, 0.58 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422307B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-e80ae00df12e44f8a4c7e3e14f82bc54 |
| Source note | uspto-grants-2016_08 |