HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 148558Generated: October 29, 2026
Dimethylformamide → 1-(trans-4-{[(5-Nitro-2-{[2-(trifluoromethoxy)benzyl]amino}pyrimidin-4-yl)amino]methyl}cyclohexyl)azetidine-2-carboxylic acid tert-butyl ester
https://huagongshe.com/reaction/148558
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | tert-Butyl 2,4-dibromobutyrate | HCID 5107723 | — |
| Reactant | N4-(4-amino-cyclohexylmethyl)-5-nitro-N2-(2-trifluoromethoxy-benzyl)-pyrimidine-2,4-diamine | HCID 16202211 | — |
| Product | 1-(trans-4-{[(5-Nitro-2-{[2-(trifluoromethoxy)benzyl]amino}pyrimidin-4-yl)amino]methyl}cyclohexyl)azetidine-2-carboxylic acid tert-butyl ester | HCID 57885676 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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| ORD ID | ord-09f48e1a0d9a4640b8daff453b81a03c |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (9/10) |
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