huagongshe.com
HRID1485646

反应详情

EQUATION

反应方程式

HRID 1485646 的结构方程式

REACTANTS

反应物

2
结构：C[Si](C)(C)CCOCn1c(O[C@@H]2CO[C@H]3[C@@H]2OC[C@H]3O)nc2cc(Cl)c(I)nc21
HCID123413447

未命名化合物

结构：CN(C)S(C)(=O)=Nc1ccc(B2OC(C)(C)C(C)(C)O2)cc1
HCID131736751

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)S(C)(=O)=Nc1ccc(-c2nc3c(cc2Cl)nc(O[C@@H]2CO[C@H]4[C@@H]2OC[C@H]4O)n3COCC[Si](C)(C)C)cc1
HCID131736752

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

The title compound is prepared from (3R,3aR,6R,6aR)-6-(6-chloro-5-iodo-3-(2-trimethylsilanyl-ethoxymethyl)-3H-imidazo[4,5-b]pyridin-2-yloxy)hexahydrofuro[3,2-b]furan-3-ol and N,N-dimethyl-N′-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-methanesulfonimidamide following a procedure analogous to that described for Intermediate 3 (Step 3) using 1,4-dioxane as a solvent. LC (method 2): tR=1.00 min; Mass spectrum (ESI+): m/z=624 [M+H]+.