HCID 118080534, compound → HCID 118080548, compound

HRID 1485791Notes

Reaction equation

HRID 1485791 reaction equation
C(N1C2C(=CC=C(N)C=2)N(C(OC(C)C)=O)C[C@@H]1C)(=O)C.[C:22]([NH:25][C:26]1[CH:27]=[C:28]2[C:33](=[CH:34][C:35]=1C1C=NN(C3CC3)C=1)[N:32]([C:44]([O:46][CH:47]([CH3:49])[CH3:48])=[O:45])[CH2:31][C@H:30]([CH3:50])[N:29]2[C:51](=[O:53])[CH3:52])(=[O:24])[CH3:23]>>[C:22]([NH:25][C:26]1[CH:27]=[C:28]2[C:33](=[CH:34][CH:35]=1)[N:32]([C:44]([O:46][CH:47]([CH3:48])[CH3:49])=[O:45])[CH2:31][C@H:30]([CH3:50])[N:29]2[C:51](=[O:53])[CH3:52])(=[O:24])[CH3:23]

Participants

3

Reactant 2

HCID 118080534HCID 118080534, compoundHCID 118080544HCID 118080544, compound

Product 1

HCID 118080548HCID 118080548, compound

Procedure

Isopropyl (S)-6-acetamido-4-acetyl-3-methyl-3,4-dihydroquinoxaline-1(2H)-carboxylate was synthesized from isopropyl (S)-4-acetyl-6-amino-3-methyl-3,4-dihydroquinoxaline-1(2H)-carboxylate according to the procedure described above for isopropyl (S)-6-acetamido-4-acetyl-7-(1-cyclopropyl-1H-pyrazol-4-yl)-3-methyl-3,4-dihydroquinoxaline-1(2H)-carboxylate (Example 235). MS (ESI, pos. ion) m/z 356 [M+Na]+.

Sources & evidence

ORD record
ord-0fc08532a66a45d583220e4f79b84089
Source dataset
uspto-grants-2016_08
Patent number
US09422281B2

Reaction notes

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