HCID 118080523, compound → HCID 118080633, compound

HRID 1485792Notes

Reaction equation

C(N1C2C(=CC=C(N)C=2)N(C(OC(C)C)=O)C[C@@H]1C)(=O)C.[C:22]([N:25]1[C:34]2[C:29](=[CH:30][C:31](C3C=NN(C4CC4)C=3)=[C:32]([NH:35][S:36]([CH3:39])(=[O:38])=[O:37])[CH:33]=2)[N:28]([C:48]([O:50][CH:51]([CH3:53])[CH3:52])=[O:49])[CH2:27][C@@H:26]1[CH3:54])(=[O:24])[CH3:23]>>[C:22]([N:25]1[C:34]2[C:29](=[CH:30][CH:31]=[C:32]([NH:35][S:36]([CH3:39])(=[O:38])=[O:37])[CH:33]=2)[N:28]([C:48]([O:50][CH:51]([CH3:53])[CH3:52])=[O:49])[CH2:27][C@@H:26]1[CH3:54])(=[O:24])[CH3:23]

Participants

Reactant 2

HCID 118080523HCID 118080523, compound

HCID 118080544HCID 118080544, compound

Product 1

HCID 118080633HCID 118080633, compound

Procedure

Isopropyl (S)-4-acetyl-3-methyl-6-(methylsulfonamido)-3,4-dihydroquinoxaline-1(2H)-carboxylate was synthesized from isopropyl (S)-4-acetyl-6-amino-3-methyl-3,4-dihydroquinoxaline-1(2H)-carboxylate according to the procedure described above for isopropyl (S)-4-acetyl-7-(1-cyclopropyl-1H-pyrazol-4-yl)-3-methyl-6-(methylsulfonamido)-3,4-dihydroquinoxaline-1(2H)-carboxylate (Example 234). MS (ESI, pos. ion) m/z 392 [M+Na]+.

Sources & evidence

ORD record: ord-37fa0fef93724f83b9ed93a16e94fa2d
Source dataset: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09422281B2

Reaction notes

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