HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 118080513, compound → HCID 118080531, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 118080513 | HCID 118080513 | — |
| Reactant | HCID 118080525 | HCID 118080525 | — |
| Catalyst | copper(I) bromide | HCID 24593 | — |
| Product | HCID 118080531 | HCID 118080531 | — |
Reaction Steps
Isopropyl (S)-4-acetyl-6-cyano-7-(1-cyclopropyl-1H-pyrazol-4-yl)-3-methyl-3,4-dihydroquinoxaline-1(2H)-carboxylate was synthesized from isopropyl (S)-4-acetyl-6-amino-7-(1-cyclopropyl-1H-pyrazol-4-yl)-3-methyl-3,4-dihydroquinoxaline-1 (2H)-carboxylate according to the procedure described above for isopropyl (S)-4-acetyl-6-bromo-3-methyl-7-(4-(methylsulfonyl)phenyl)-3,4-dihydroquinoxaline-1(2H)-carboxylate (Example 238), substituting copper (I) cyanide for copper (I) bromide. MS (ESI, pos. ion) m/z 408 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09422281B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-821cd7fd428e4572b83ed0e1eaa81e74 |
| Source note | uspto-grants-2016_08 |