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HRID1486081

反应详情

EQUATION

反应方程式

HRID 1486081 的结构方程式

REACTANTS

反应物

1
结构：C[C@H](N=[N+]=[N-])[C@H](NC(=O)OC(C)(C)C)C(=O)OCc1ccccc1
HCID131736777

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](N)[C@H](NC(=O)OC(C)(C)C)C(=O)O
HCID90079392

未命名化合物

收率 103.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

A solution of (2S,3S)-benzyl 3-azido-2-(tert-butoxycarbonylamino)butanoate (1.7 g, 5.08 mmol) and PdC (5%, wet) (340 mg, 319 μmol) in MeOH (16.4 g, 20.7 ml) was shaken under H2 (50 PSI) for 3.5 h, then filtered through a bed of celite and concentrated to give (2S,3S)-3-amino-2-(tert-butoxycarbonylamino)butanoic acid (1.15 g, quant.) as a white solid.

WORKUP

后处理

  1. filtrationfiltered through a bed of celite and
  2. concentrationconcentrated