Sulfuric Acid → HCID 90021602, compound

Participants

Reaction Steps

A 250 mL 1-neck flask was equipped with a magnetic stirrer and a reflux condenser with nitrogen blanket. The flask was charged with 6.52 grams (0.025 moles) of trityl alcohol, 3.77 grams (0.025 moles) of o-sec-butylphenol, and 50 mL of glacial acetic acid. The mixture was stirred under nitrogen at room temperature to give a clear, yellow solution. Concentrated sulfuric acid (5 mL) was then added in one portion. The solution immediately became dark red-brown. The solution was stirred at room temperature for 2 days, during which time solids separated out. The reaction mixture was filtered, and the solids were washed on the filter with several portions of water. After drying in a vacuum oven at 65° C. for 3 hours, the yield of product was 7.34 grams (75% yield). MP=135-136° C. GPC analysis showed a purity of >99%. The structure was confirmed by IR, 1H- and 13C-NMR analyses.

Provenance & Evidence