(2S)-2-amino-2-cyclopropylacetic acid → (S)-2-Cyclopropyl-2-((methoxycarbonyl)amino)acetic acid

HRID 1486403Notes

Reaction equation

HRID 1486403 reaction equation
[CH3:1][O:2][C:3]([NH:5][C@H:6]([C:10]([OH:12])=[O:11])[CH:7]([CH3:9])[CH3:8])=[O:4].C1C([C@H](N)C(O)=O)C1>>[CH:7]1([C@H:6]([NH:5][C:3]([O:2][CH3:1])=[O:4])[C:10]([OH:12])=[O:11])[CH2:9][CH2:8]1

Participants

3

Reactant 2

HCID 1501944(2S)-2-amino-2-cyclopropylacetic acidHCID 10942966(2S)-2-((methoxycarbonyl)amino)-3-methylbutanoic acid

Product 1

HCID 59610985(S)-2-Cyclopropyl-2-((methoxycarbonyl)amino)acetic acid

Procedure

(S)-2-cyclopropyl-2-(methoxycarbonylamino)acetic acid was synthesized similar to N-methoxycarbonyl-L-Valine, using L-cyclopropylglycine instead of L-Valine.

Sources & evidence

ORD record
ord-a0243590276b4e888e03dfa9183f3281
Source dataset
uspto-grants-2016_08
Patent number
US09427428B2

Reaction notes

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