HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Acetyl-4-methoxyphenylboronic acid → tert-butyl 2-(2-acetyl-4-methoxyphenyl)-3-cyclohexyl-1H-indole-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Acetyl-4-methoxyphenylboronic acid | HCID 57801700 | — |
| Reactant | tert-butyl 2-(4-chloro-2-formylphenyl)-3-cyclohexyl-1H-indole-6-carboxylate | HCID 86652976 | — |
| Product | tert-butyl 2-(2-acetyl-4-methoxyphenyl)-3-cyclohexyl-1H-indole-6-carboxylate | HCID 68340203 | — |
Reaction Steps
The title product tert-butyl 2-(2-acetyl-4-methoxyphenyl)-3-cyclohexyl-1H-indole-6-carboxylate 37d was synthesized by following a similar procedure to that used for the synthesis of tert-butyl 2-(4-chloro-2-formylphenyl)-3-cyclohexyl-1H-indole-6-carboxylate 34b, using 2-acetyl-4-methoxyphenylboronic acid 37c instead of 4-chloro-2-formylphenylboronic acid 34a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09427440B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-8a2a318e4c2f4fb8ae582d0244757741 |
| Source note | uspto-grants-2016_08 |