反应详情

Tert-butyl 4-(3-(3,5-dichlorophenylamino)-1H-1,2,4-triazol-5-ylamino)piperidine-1-carboxylate (180 mg, 0.42 mmol) was dissolved in 30% TFA/methylene chloride (10 mL) and the mixture was stirred at rt for 30 min. Removal of solvent under reduced pressure gave a solid, which was washed with diethyl ether (10 mL) to give 178 mg (96%) of desired product as an off-white solid. MS +m/z: 327.0 (M+H)+

1. customRemoval of solvent under reduced pressure
2. customgave a solid, which
3. washwas washed with diethyl ether (10 mL)