trans-2-Decenoic acid → HCID 72189333, compound

HRID 1486634Notes

Reaction equation

HRID 1486634 reaction equation
[C:1]([OH:12])(=[O:11])/[CH:2]=[CH:3]/[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].Cl.Cl.[N:15]1([CH2:21][C:22]2[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][CH:23]=2)[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]1>>[C:1]([N:18]1[CH2:17][CH2:16][N:15]([CH2:21][C:22]2[CH:31]=[CH:30][C:25]([C:26]([O:28][CH3:29])=[O:27])=[CH:24][CH:23]=2)[CH2:20][CH2:19]1)(=[O:12])/[CH:2]=[CH:3]/[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[C:1]([N:18]1[CH2:19][CH2:20][N:15]([CH2:21][C:22]2[CH:31]=[CH:30][C:25]([C:26]([OH:28])=[O:27])=[CH:24][CH:23]=2)[CH2:16][CH2:17]1)(=[O:11])/[CH:2]=[CH:3]/[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

4

Reactant 2

HCID 5282724trans-2-Decenoic acidHCID 20232499HCID 20232499, compound

Product 2

HCID 72189333HCID 72189333, compoundHCID 117920119HCID 117920119, compound

Procedure

The same procedures as in Example 2 were carried out using (E)-2-decenoic acid and methyl 4-[1-piperazinylmethyl)benzoate dihydrochloride as starting raw materials, to produce methyl 4[[4-((E)-2-decenoyl)piperazin-1-yl]methyl]benzoate (methyl ester of Compound 48).

Sources & evidence

ORD record
ord-455c3e7adc6144a2832de8ab42985dd2
Source dataset
uspto-grants-2016_08
Patent number
US09428477B2

Reaction notes

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