trans-2-Decenoic acid → 4-[(E)-2-Decenoyl]morpholine-3-carboxylic acid

HRID 1486635Notes

Reaction equation

HRID 1486635 reaction equation
[C:1]([OH:12])(=[O:11])/[CH:2]=[CH:3]/[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].Cl.[NH:14]1[CH2:19][CH2:18][O:17][CH2:16][CH:15]1[C:20]([O:22][CH3:23])=[O:21]>>[C:1]([N:14]1[CH2:19][CH2:18][O:17][CH2:16][CH:15]1[C:20]([O:22][CH3:23])=[O:21])(=[O:12])/[CH:2]=[CH:3]/[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[C:1]([N:14]1[CH2:19][CH2:18][O:17][CH2:16][CH:15]1[C:20]([OH:22])=[O:21])(=[O:11])/[CH:2]=[CH:3]/[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

Participants

4

Reactant 2

HCID 5282724trans-2-Decenoic acidHCID 42614243Methyl morpholine-3-carboxylate hydrochloride

Product 2

HCID 721893344-[(E)-2-Decenoyl]morpholine-3-carboxylic acidHCID 117920449methyl 4-[(E)-2-decenoyl)morpholine-3-carboxylate

Procedure

The same procedures as in Example 2 were carried out using (E)-2-decenoic acid and methyl morpholine-3-carboxylate hydrochloride as starting raw materials, to produce methyl 4-[(E)-2-decenoyl)morpholine-3-carboxylate (methyl ester of Compound 49).

Sources & evidence

ORD record
ord-06a6cce71826434a9b9a7db82f3e2db9
Source dataset
uspto-grants-2016_08
Patent number
US09428477B2

Reaction notes

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