HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67085659, compound → 5-Cyclopropylpyridine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67085659 | HCID 67085659 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Cyclopropylpyridine-2-carboxylic acid | HCID 57827722 | — |
Reaction Steps
To a solution of benzyl 5-cyclopropylpicolinate in MeOH (15 mL) was added 20% Pd(OH)2/C (100 mg). The hydrogenolysis with H2 was carried out at room temperature under a H2 balloon. The desired product 5-cyclopropylpicolinic acid (305 mg) was obtained after filtration and concentration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428475B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-d0c7c210dcba46fca2ca9ec989e4ba4c |
| Source note | uspto-grants-2016_08 |