HRID1486675

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID79257

Chloromethyl benzoate

C8H7ClO2

结构：C=CCOC(=O)N1COC(=O)[C@]12[C@H]1[C@@H](C[C@@H]2F)[C@@H]1C(=O)O

HCID117987522

未命名化合物

PRODUCTS

生成物

结构：N[C@]1(C(=O)O)[C@H]2[C@@H](C[C@@H]1F)[C@@H]2C(=O)OCOC(=O)c1ccccc1

HCID72550543

未命名化合物

收率 35.1%

PROCEDURE

实验过程

(1S,2S,3S,5R,6S)-3′-((Allyloxy)carbonyl)-3-fluoro-5′-oxospiro[bicyclo[3.1.0]hexan-2,4′-oxazolidine]-6-carboxylic acid (A-1-2, 500 mg) and chloromethyl benzoate (712 mg) were treated in the same manner as in Example A-1 (3) and (4) to give the title compound (A-9, 198 mg) as a colorless solid.