HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrobenzaldehyde → HCID 86706530, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrobenzaldehyde | HCID 7449 | — |
| Reactant | HCID 43272163 | HCID 43272163 | — |
| Reactant | HCID 86706531 | HCID 86706531 | — |
| Product | HCID 86706530 | HCID 86706530 | — |
Reaction Steps
The title compound is prepared according to the reactions described above starting from 3-nitro-benzaldehyde and piperidine-4-carboxylic acid isobutyl-methyl-amide yielding after reductive amination 1-(3-nitro-benzyl)-piperidine-4-carboxylic acid isobutyl-methyl-amide; LC-MS A: tR=0.61 min; [M+H]+=366.35 followed by reduction with stannous chloride the title compound LC-MS A: tR=0.48 min; [M+H]+=304.24.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09428456B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-e60ca1d1f2554e7da83dac20fd0787d2 |
| Source note | uspto-grants-2016_08 |