n-Cyclohexylpiperidine-4-carboxamide → HCID 86706534, compound

HRID 1486702Notes

Reaction equation

HRID 1486702 reaction equation
Cl[CH2:2][C:3]1[N:8]=[C:7]([NH2:9])[CH:6]=[CH:5][N:4]=1.[CH:10]1([NH:16][C:17]([CH:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)=[O:18])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1>>[CH:10]1([NH:16][C:17]([CH:19]2[CH2:20][CH2:21][N:22]([CH2:2][C:3]3[N:8]=[C:7]([NH2:9])[CH:6]=[CH:5][N:4]=3)[CH2:23][CH2:24]2)=[O:18])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]1

Participants

3

Reactant 2

HCID 12410238n-Cyclohexylpiperidine-4-carboxamideHCID 212988272-(Chloromethyl)pyrimidin-4-amine

Product 1

HCID 86706534HCID 86706534, compound

Procedure

The title compound is prepared according to the reactions described above starting from 2-chloromethyl-pyrimidin-4-ylamine and piperidine-4-carboxylic acid cyclohexylamide; LC-MS A: tR=0.47 min; [M+H]+=318.12.

Sources & evidence

ORD record
ord-a564e6e6e6fc42c39060d9e6466940f2
Source dataset
uspto-grants-2016_08
Patent number
US09428456B2

Reaction notes

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