HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-cyclopentylpiperidine-4-carboxamide → [4-(4-Cyclopentylcarbamoyl-piperidin-1-ylmethyl)-thiazol-2-yl]-carbamic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-cyclopentylpiperidine-4-carboxamide | HCID 17604582 | — |
| Edukt | (4-Formylthiazol-2-yl)carbamic acid tert-butyl ester | HCID 23138686 | — |
| Produkt | [4-(4-Cyclopentylcarbamoyl-piperidin-1-ylmethyl)-thiazol-2-yl]-carbamic acid tert-butyl ester | HCID 131736799 | — |
Reaktionsschritte
The title compound is prepared according to the reactions described above starting from (4-formyl-thiazol-2-yl)-carbamic acid tert-butyl ester and piperidine-4-carboxylic acid cyclopentylamide J-4 yielding after reductive amination [4-(4-cyclopentylcarbamoyl-piperidin-1-ylmethyl)-thiazol-2-yl]-carbamic acid tert-butyl ester; LC-MS A: tR=0.66 min; [M+H]+=409.13.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09428456B2 |
| Quelldatensatz | uspto-grants-2016_08 |
| ORD ID | ord-7733418cccc04e13bc86accd51451c8e |
| Quellennotiz | uspto-grants-2016_08 |