N-tert-butylpiperidine-4-carboxamide → HCID 86706543, compound

Participants

Reaction Steps

The title compound is prepared according to the reactions described for BB-5 above starting from 2-methoxy-3-nitro-benzaldehyde and piperidine-4-carboxylic acid tert-butylamide yielding after reductive amination 1-(2-methoxy-3-nitro-benzyl)-piperidine-4-carboxylic acid tert-butylamide; LC-MS A: tR=0.61 min; [M+H]+=350.22 followed by reduction with stannous chloride the title compound; LC-MS A: tR=0.52 min; [M+H]+=320.27.

Provenance & Evidence